[Press Release]Discovery of a new mechanism by which changes in the distance between genes regulate their expression

Drs Hiroaki Oishi, Hiroshi Ochiai, (Kyushu University, respectively) and Soya Shinkai et al. found a novel mechanism of gene expression regulation involving changes in the spatial distance between genes. Understanding the mechanisms of gene expression regulation is crucial not only for molecular biology but also for medical research, as it directly links to identifying disease causes and therapeutic targets.

Learn more about the study on Press Release by Kyushu University, RIKEN and JST. (In Japanese only)

Reference

Ohishi, H., Shinkai, S., Owada, H., Fujii, T., Hosoda, K., Onami, S., Yamamoto, T., Ohkawa, Y., Ochiai, H. (2024). Transcription-coupled changes in genomic region proximities during transcriptional bursting. Sci. Adv. 10, eadn0020. DOI:10.1126/sciadv.adn0020