[Press Release] Steady-state chromatin motion throughout interphase

Drs. Soya Shinkai and Shuichi Onami together with Shiori Iida (SOKENDAl) and Prof. Kazuhiro Maeshima (NIG) et. al. have investigated the local movements of chromatin in living human cells using super-resolution fluorescence microscopy.

Learn more about the study on Press Release from the National Institute of Genetics.


Iida S., Shinkai, S., Itoh, Y., Tamura, S., Kanemaki, M. T., Onami, S., Maeshima, K. (2022). Single-nucleosome imaging reveals steady-state motion of interphase chromatin in living human cells. Sci. Adv. 8, eabn5626.


Article Update

SSBD was featured in the Singularity Biology News Letter No.4.

Dr Onami in Experimental Medicine.

A contribution by Dr Onami, “Development of data format standards and data sharing systems for bioimaging” has been published in a magazine, Experimental Medicine.

Texture-Based Screening to Identify Genes Involved in Reproductive Aging in C. elegans

Dr Momoko Imakubo et al.’s study on analysis of genes involved in reproductive aging in C. elegans oocytes by using an image database of RNAi embryos and image processing has been published online at https://doi.org/10.17706/ijbbb.2021.11.3.40-49.

Congratulations to our former student trainee Momoko Imakubo who earned her PhD from Kobe University in March 2021 on her achievement. We wish you all the best in your future endeavour!

New Paper by Momoko Imakubo

A new paper by Momoko Imakubo, Student Trainee in the Onami lab, was published in the BMC Bioinformatics.

In this paper, we quantified age-associated changes in oocyte appearance in the nematode Caenorhabditis elegans by statistical image processing. We showed that the oocyte cytoplasmic texture in Nomarski differential interference contrast images significantly changes with aging.


Paper Published by Dr. Yamagata

Dr. Yuki Yamagata, Research Scientist in the Onami lab, co-authored a review paper with Dr. Hiroshi Masuya, RIKEN BRC, et al. The paper was published in the January issue of Laboratory Animal Research.

The RIKEN BioResource Research Center released an integrated database of bioresources including, experimental mouse strains, Arabidopsis thaliana as a laboratory plant, cell lines, microorganisms, and genetic materials using Resource Description Framework-related technologies in 2020. This review summarizes the features of current version of databases related to mouse strain resources in RIKEN BioResource Research Center and discusses future views. 


TL’s talk in Symposium went public

Team Leader Dr. Onami attended an online open symposium “
Prospects for next-generation integrated bioimaging and mathematical collaboration” which was organized by the Science Council of Japan in October. His presentation is now available online.

This symposium was aimed to discuss a theme: ” Will the advanced fusion of imaging technology and mathematical/ information science lead to a paradigm shift in life science? ” in Japan with not only researchers in the field of advanced bioimaging measurement but also researchers in a wide range of fields such as mathematics, physics, and information science.

To watch his talk visit our multimedia page.

Other presentations and discussions are available on the symposium website. The website and all videos were only in Japanese.